Apresentação de Casos April 01, 2002 April 01, 2002

Hypothalamic-Pituitary-Adrenal Suppression and Risk of Secondary Adrenal Insufficiency Due to Use of Nasal Dexamethasone

DOI: 10.1590/S0004-27302002000200013

Corticosteroid use is an important cause of secondary adrenal insufficiency and some authors do not consider nasal use as able to cause it. Rhinitis is a usual disease and corticosteroid has been used with good results, with no association to its possible systemic effects. The authors report two cases of secondary adrenal insufficiency caused by nasal dexamethasone. Some aspects of this peculiar condition are discussed.