Letter to the editor November 17, 2022 November 17, 2022

Response to the letter to the editor: two cases of subacute thyroiditis after different types of SARS-CoV-2 vaccination

DOI: 10.20945/2359-3997000000569

DEAR EDITORS AND COLLEAGUES,

We would like to thank Mungmunpuntipantip and Wiwanitkit for their comments and contributions to our article “Two cases of subacute thyroiditis after different types of SARS-CoV-2 vaccination” (). They commented on the possible mechanisms of vaccine-associated subacute thyroiditis (SAT) and emphasized that subclinical thyroid disorders in the pre-vaccine period should be excluded. We do agree that the exclusion of subclinical thyroid problems is a factor that strengthens the possible relationship. We would like to emphasize that these patients were euthyroid in their routine follow-up visits before the vaccination. In our article, we mentioned that both cases did not have any known thyroid or autoimmune disorder before the coronavirus disease 2019 (COVID-19) vaccination. However, recently, cases of SAT, Graves’ disease (GD) relapses, and even conversion from Hashimoto’s disease to GD have been reported after the COVID-19 vaccination (,). This raises the question that vaccination may be a triggering factor for relapse in patients with pre-existing autoimmune/inflammatory thyroid disorders.

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