OBJECTIVES: Our aim was to analyze measures taken to increase the radiation absorbed dose (DOSE) during treatment of well-differentiated thyroid cancer (DTC) with iodine-131. METHODS: An increase in DOSE is achieved by: avoiding competition with non-radioactive iodine, stimulating cellular uptake/retention, increasing the administered activity. Basis and results of each one of these methods were reviewed. RESULTS: Although it is difficult to demonstrate an increase in survival, there is a direct relation between DOSE and tumoral response in DTC. Different approaches […]

INTRODUCTION: Carbohydrate counting is probably the most precise and flexible meal planning approach available, especially for those with type 1 diabetes (DM1). OBJECTIVE: To evaluate the degree of satisfaction of that approach in patients treated by intensive insulin therapy. METHODS: 50 DM1 patients submitted to carbohydrate counting for 6 months answered a questionnaire related to the lifestyle. RESULTS: The answers were favorable in: >80% to requirements related to the choice of the number of meals, to eat out, schedules of […]

Long-term treatment of obese patients shows that the majority of them regains weight or has weight cycling (WC). We have studied the frequency of WC (weight lost and regain of at least 5% of initial weight, IW) in 218 obese women selected from a University Hospital with a follow-up of >12 months admitted between 1992 and 2000. Patients with psychiatric, infectious or chronic disease (except metabolic syndrome), pregnancy, or using glucocorticoids were excluded. Mean age was 38±10 years (range 18 […]

In the present paper, hyperuricemia was analyzed in nine obese women with body mass index (BMI) >35kg/m2, while receiving a very low calorie diet (400/600kcal/day) for 6 weeks. The first two weeks were for clinical diagnosis and diet adaptation. Serum uric acid and ketonuria were measured weekly, and on the 4th week total uric acid urinary excretion was also determined. The mean (±SD) BMI were 54±12 and 49±11kg/m2, respectively at admission and discharge, corresponding to a body weight loss of […]