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DOI: 10.1590/S0004-27302002000400004
One of the major actions of hormonal stimuli is the modulation of the expression of the genes. Since the rate of gene transcription is the major determinant of gene expression, the molecular mechanisms by which gene transcription are regulated have gained increasing interest and has become a major topic in Molecular Endocrinology. In this paper, the authors critically reviewed both the theoretical aspects and the applications of the techniques mostly used in the studies of gene transcription. The advantages and […]
Keywords: DNA-binding proteins; Gene expression regulation; Genetic transcription; Promoter regions; transcription factors