OBJECTIVE: To better explore the relationship between parameters of glycemic control of T2DM in RRT, we studied 23 patients on hemodialysis (HD), 22 on peritoneal dialysis (PD), and compared them with 24 T2DM patients with normal renal function (NRF). MATERIALS AND METHODS: We performed, on four consecutive days, 10 assessments of capillary blood glucose [4 fasting, 2 pre- and 4 postprandial (post-G) and average (AG)], random glycemia, and HbA1c in all patients. RESULTS: Preprandial blood glucose was greater in patients […]

Diabetic nephropathy (DN) is the main cause of chronic kidney disease (CKD) in developed countries. OBJECTIVE: To observe if there was an increase in the prevalence of diabetes mellitus (DM) of CKD in the last 20 years and to analyze comparatively the survival on dialysis of diabetic and non-diabetic patients. METHODS: Retrospective analysis of patients kept on dialysis in the west region of Paraná State in the period between 1985

Angiotensin II antagonists (AIIAs) were introduced to treat hypertension about 10 years ago. During this period they were evaluated not only in terms of efficacy and safety but also in several large studies with clinical outcomes. They are efficacious in all clinical forms of hypertension and are effective also in all ethnic groups. Cardiovascular and renal protection in proteinuric diabetic nephropathy beyond blood pressure reduction was proved in major clinical studies: Losartan Intervention For Endpoint reduction in hypertension study (LIFE), […]