Abstract Objective: This study aimed to evaluate extracellular vesicles (EVs) in a group of carriers of familial hypercholesterolemia (FH)-related genetic variants compared to those in family members without FH. Subjects and methods: Annexin V-positive EVs (PS+-EVs), cardiomyocyte-derived EVs (CardioEVs), endothelial cell-derived EVs (EEVs), platelet-derived EVs (PEVs) and tissue factor-expressing EVs (TFEVs) were evaluated to compare individuals with FH and genetic variants (n = 16) and non-FH patients without genetic variants (n = 16). Results: Increased numbers of PS+-EVs, CardioEVs, EEVs […]
