Abstract Objective: To identify cytologic characteristics in a suspicious for malignancy cohort that may help to recognize false positives in cytopathological tests of thyroid nodules in a “real world scenario”, with histopathological reports as the gold standard. Methods: Cytomorphologic features of suspicious for malignancy thyroid nodules in a 13-year retrospective database were reviewed. Therefore, we identified false positive cases, analyzed the possible causes of cytopathological diagnostic failure and calculated the frequency of false positive results and the risk of malignancy […]