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DOI: 10.1590/S0004-27302006000400024
Glucocorticoid-induced osteoporosis is the most frequent cause of secondary osteoporosis. Glucocorticoids cause a rapid bone loss in the first few months of use, but the most important effect of the drug is suppression of bone formation. The administration of oral glucocorticoid is associated with an increased risk of fractures at the spine and hip. The risk is related to the dose, but even small doses can increase the risk. Patients on glucocorticoid therapy lose more trabecular than cortical bone and […]
Keywords: epidemiology; Fractures/risk factors; Glucocorticoid/adverse reactions; Osteoporosis; review