Thyrotoxicosis is confirmed by high serum total or free triiodothyronine (T3/FT3) and thyroxine (T4/FT4) and low serum thyrotropin (TSH) concentrations. In endemic areas, a predominant increase of T3 with normal or low T4 and FT4 can be found, referred to as “T3-thyrotoxicosis”. One variant, known as “free T3-toxicosis” has recently been described presenting subnormal serum TSH, normal FT4 and total T3 concentrations, but high serum FT3. Thyrotoxicosis increases bone turnover, especially resorption, with bone loss and increases fracture rates; involves […]