1 results
DOI: 10.1590/S0004-27302006000600014
Galectin-3 is a multifunctional protein highly expressed in thyroid cancer. The galectin-3 gene (LGALS3) has several annotated candidates SNPs, however the relationship between galectin-3 SNPs and specific phenotypic variations relevant to health has not been evaluated. In this study, we investigated SNPs in the galectin-3 gene and a putative association with thyroid tumorigenesis. The presence of LGALS3 SNPs in thyroid carcinoma cell lines (NPA, TPC-1, WRO, ARO), thyroid tissues of 55 patients with multinodular goiter or papillary carcinoma diagnosis and […]
Keywords: Galectin-3; LGALS3; Sequencing; single nucleotide polymorphism (SNP); Single-strand conformation polymorphism (SSCP); Thyroid cancer