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DOI: 10.1590/S0004-27302003000600004
Thyroid hormones play an important role on growth, development and metabolism of all vertebrates. Serum concentration of thyroid hormones are controlled by TRH, somatostatin and TSH which determine the rate of hormone biosynthesis and release, as well as by deiodinases (mainly type I), enzymes which generate in peripheral tissues, approximately 75% of the T3 present in serum, from circulating T4; type II deiodinases, on the other hand, are supposed to generate T3 for the tissues in which they are expressed. […]
Keywords: Biological effects; Deiodinases; Genomic actions; Non-genomic actions; Target genes; Thyroid hormones