ABSTRACT Objective The aim of this study was to verify the effects of glycemic index (GI) on body composition, and on inflammatory and metabolic markers concentrations in patients with type 2 diabetes. Subjects and methods In this randomized controlled parallel trial, twenty subjects (aged 42.4 ± 5.1 years, BMI 29.2 ± 4.8 kg.m-2) were allocated to low GI (LGI) (n = 10) or high GI (HGI) (n = 10) groups. Body composition, inflammatory and metabolic markers were assessed at baseline […]

Objective Evaluate the effect of glycemic index (GI) on biochemical parameters, food intake, energy metabolism, anthropometric measures and body composition in overweight subjects. Materials and methods Simple blind study, in which nineteen subjects were randomly assigned to consume in the laboratory two daily low GI (n = 10) or high GI (n = 9) meals, for forty-five consecutive days. Habitual food intake was assessed at baseline. Food intake, anthropometric measures and body composition were assessed at each 15 days. Energy […]

OBJECTIVE: To assess the influence of a non-pharmacological intervention, consisting of a diet low glycemic index (GI) for a period of six months on metabolic control and anthropometric parameters in patients with type 1 diabetes mellitus. SUBJECTS AND METHODS: Ninety-six type 1 diabetic patients underwent an anthropometric, biochemical and dietary assessment before and six months after the prescription of diet based on the glycemic index. RESULTS: After six months we observed a decrease in A1C levels (9,8 ± 2,26% vs. […]

The tight glycemic control can prevent and/or delay the development of chronic complications of diabetes mellitus (DM). Dietary carbohydrates are the main determinant of postprandial blood glucose and glycemic index (GI) and glycemic load are used to predict blood glucose response to foods. The aim of this paper was to critically review the role of low GI diets in type 2 diabetes mellitus (T2DM) prevention and metabolic control. The risk for development of T2DM with high GI diets ranged from […]

OBJECTIVE: To investigate the association between carbohydrate intakes and ?-cell function (HOMA-?) in Japanese-Brazilians with impaired glucose tolerance (IGT). METHODS: Dietary intakes were assessed by a validated food frequency questionnaire in a cross-sectional survey carried out in 2000. The associations between diet and HOMA-? were verified in 270 newly diagnosed IGT in multiple linear regression models. RESULTS: The mean (SD) age was 58 (11) years and the mean HOMA-? was 65 (47). The glycemic load was inversely associated with HOMA-?, […]

OBJECTIVES: Through the analysis of a group of type 2 diabetes patients, the aims of this study are: to evaluate through CGMS (continuous glucose monitoring system) the post-prandial subcutaneous glucose excursions; to analyze the correlations between subcutaneous glucose and capillary glycemia with HbA1c and to evaluate the effectiveness, safety and broadmindedness of the CGMS. METHODS: Forty type 2 diabetes patients were analyzed, with HbA1c until 7.3%, in use of oral agents and within less than a ten-year diagnosis. They were […]

The prevalence of obesity has increased over the last decades. Associated to this, there has been observed a chance in the dietetic pattern of the population in general, related to the increase in carbohydrate consumption. According to some authors, the glycemic index (GI) of food may affect body composition and body weight. The purpose of this review was to evaluate the effects of GI on appetite, satiety, and body composition. Based on the scientific evidences reviewed, it was possible to […]

The prevalence of type 2 diabetes has been escalating throughout the world and usual food consumption is regarded as one of the most important environmental determinants for chronic diseases. Thus, the role of type and quality of carbohydrates on the etiology of type 2 diabetes is still poorly understood. The present review discusses the available epidemiological evidence regarding the effect of the type and source of carbohydrate of the usual diet and the risk of type 2 diabetes in adults. […]