BACKGROUND: Our intention is to describe the clinical profile of the candidates for islet transplantation in Curitiba, Brazil. METHODS: The clinical evaluation was organized in stages: Screening, Initial Evaluation, Evaluation and Waiting List. Candidates’ inclusion criteria were hypoglycemia unawareness, glycemic imbalance, chronic progressive diabetic complications, 18-65 years of age and at least 5 years of type 1 diabetes evolution. RESULTS: From September 2003 through September 2006, 92 candidates were clinically evaluated, and 25 fulfilled the Screening criteria, being selected at […]

The authors after presenting the magnitude of the problem of diabetes mellitus and diabetic nephropathy in Brazil and in the world made a review upon the point of view of the nephrologist about pancreas and pancreatic islet transplantation centered on the risks and benefits of the simultaneous pancreatic kidney transplantation (SPKT) for the diabetic with end-stage renal failure. In the paper it is stressed the importance of the interaction between the endocrinologist and the nephrologist for improving the survival of […]