ABSTRACT Objective To investigate the prognostic significance of thyroid hormone profile in patients hospitalized for decompensated cirrhosis. Subjects and methods Prospective cohort study that included 119 subjects. All subjects were evaluated at admission and followed for 90 days. TSH, fT3, fT4 were measured within 24 hours of hospitalization. Results Higher fT4 and lower fT3 levels were observed among Child-Pugh C patients as compared to Child-Pugh A and B, and in those with acute-on-chronic liver failure (ACLF). Lower fT3/fT4 ratio was […]

ABSTRACT The management of diabetes mellitus (DM) requires maintaining glycemic control, and patients must keep their blood glucose levels close to the normal range to reduce the risk of microvascular complications and cardiovascular events. While glycated hemoglobin (A1C) is currently the primary measure for glucose management and a key marker for long-term complications, it does not provide information on acute glycemic excursions and overall glycemic variability. These limitations may even be higher in some special situations, thereby compromising A1C accuracy, […]

Liver cirrhosis (LC) is one of the chronic diseases associated to hypogonadism (HG), which has a varied etiology in relation to the target organ of the gonadal axis affected. We evaluated 82 patients with LC of different etiologies, to ascertain the prevalence of HG. Non-physiological HG was diagnosed in 63 cases (76,8%). This diagnosis was initially established on clinical bases. In men, loss of libido (68,8%), erectile dysfunction (53,8%), female distribution of pubic hair (53,1%), testicular atrophy (55,3%), and gynecomastia […]