OBJETIVE: Systematic review of present knowledge about the association between diabetes mellitus (DM) and periodontal disease (PD) with emphasis on their physiopathogenesis. DATA SOURCES: Bibliographic search through MEDLINE and LILACS databases, in the last five years, using the following descriptors: “diabetes mellitus”, “periodontal disease”, and “periodontitis”. SUMMARY OF DATA: Periodontal tissues are the oral structures most affected by DM. DM predisposes to the development of PD, which leads to loss of glycemic control, which emphasizes the importance of the two-way […]