BACKGROUND AND OBJECTIVES: Studies investigating the molecular pathogenesis of common thyroid neoplasms have shown some association between oncogenes expression and histological aggressiveness of thyroid tumors. We have investigated molecular changes in variants of thyroid papillary carcinoma (TPC), by analyzing the expression of proteins related to its tumorigenesis, and further, its own relationship to the prognosis. METHODS: We examined 32 surgical specimens of TPC obtained from 5 males and 27 females (mean ages of 52.6 and 46.5 years, respectively). Monoclonal antibodies […]
