Arq Bras Endocrinol Metab 2009;53(2):145-150
Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis
DOI: 10.1590/S0004-27302009000200005
The authors analyze insulin resistance, the metabolic syndrome and endothelial dysfunction as consequence of a common antecedent, a low grade inflammation, indicating that in obesity there is a chronically activated inflammatory state of the adipose tissue. Furthermore, the inflammatory signaling is discussed according to the adipose tissue depot, visceral or subcutaneous.
Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis