Arq Bras Endocrinol Metab 2008;52(2):322-333

C-peptide residual secretion makes difference on type 1 diabetes management?

Melanie
Rodacki
, Adolpho
Milech
, José Egídio Paulo de
Oliveira

DOI: 10.1590/S0004-27302008000200020

Type 1 diabetes is a chronic disease characterized by progressive destruction of the pancreatic b cells, what leads to insulin deficiency and hyperglycemia. However, a significant secretory function may persist for long periods in a few patients, what is clinically evident through the detection of serum C peptide. This phenomenon might reduce the risk of chronic complications, severe hypoglycemias and allow easier metabolic control. It is possible that these advantages are caused, at least partially, by C peptide itself, acting directly in its target tissues.

C-peptide residual secretion makes difference on type 1 diabetes management?

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