Letter to the editor October 08, 2025 October 08, 2025

Comment on: Stress-induced hyperglycemia and expression of glucose cell transport genes in skeletal muscle of critically ill patients: a cross-sectional study

DOI: 10.20945/2359-4292-2025-0321

Dear Editor,

We read with interest the paper by Bellaver and cols., entitled “Stress-induced hyperglycemia and expression of glucose cell transport genes in skeletal muscle of critically ill patients: a cross-sectional study” (). This research provides useful information about metabolic changes in critical illness. The author presents a variety of perspectives with fairness and detail, maintaining a praiseworthy balance. We agree with the well-founded conclusion that IRS1 was downregulated in patients with stress-induced hyperglycemia; however, some methodological weaknesses have been encountered, which deserve mention.

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