Arq Bras Endocrinol Metab 2009;53(5):519-527
Dietary intake and dyslipidemia arising from combination antiretroviral therapy for HIV infection: a systematic review
DOI: 10.1590/S0004-27302009000500005
To review and synthesize the available scientific evidence on the relationship between dietary intake and dyslipidemias in HIV-infected patients in combination antiretroviral therapy (ART). A systematic review of literature was carried out. Original and published studies were investigated and two categories of dietary exposure were considered: energy and nutrient intake, and consumption of a test diet. A narrative review of included studies was conducted. The findings were summarized according to category of metabolic outcomes (effect on total cholesterol and LDL-c, effect on HDL-c and effect on triglycerides). Twenty original studies were included in this review, being 13 clinical trials and 7 observational studies. ?-3 fatty acid supplementation led to a significant decrease in triglycerides. There was very little evidence on the effectiveness of dietary interventions for the prevention and control of dyslipidemias in HIV-infected patients receiving ART.
Keywords: AIDS; diet; dyslipidemias; Food consumption; HIV; Lipodystrophy syndrome HIV