editorials April 01, 2016 April 01, 2016

Elevated irisin and alanine aminotransferase levels in hypothyroidism: role of oxidative stress?

DOI: 10.1590/2359-3997000000166

In this issue of Archives of Endocrinology and Metabolism, two articles help to increase our knowledge about the connections between thyroid status and energy metabolism. Although the relation between thyroid disease with obesity and metabolic dysfunction has been well established for many decades, some of their linking mechanisms are surprisingly still poorly understood.

In the first paper, a cross-sectional observational study, Ates and cols. () measured irisin levels of 37 patients with newly diagnosed hypothyroidism (and a mean TSH of 13.1 mIU/L) and 37 healthy volunteers.

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