Arch. Endocrinol. Metab. 2018;62(5):493-494
Metabolomics of thyroid nodules and the future
DOI: 10.20945/2359-3997000000080
In this issue of the Archives of Endocrinology and Metabolism (AE&M), the use of 3T Magnetic Resonance Spectroscopy (MRS) for the evaluation of patients with thyroid nodules (TNs) is addressed in a very interesting prospective study by Aghaghazvini and cols ().
The new field in biological science, Metabolomics, makes use of analytical and standard recognition approaches and bioinformatics (,). The metabolome is the final downstream product of gene expression reflecting changes in transcriptome and proteome (). Metabolic, histological and cytological changes occur during the development and progression of carcinoma (), and it is paramount to understand its biochemistry to allow the development of powerful diagnostic tools and to identify new biomarkers (). Several studies have demonstrated that the metabolomics makes it possible to characterize different types of tumors in other organs than thyroid gland ().
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